| Genome | |
|---|---|
| Ensembl | Genome databases for vertebrates and other eukaryotic species. |
| MITOMAP | A curated repository of published and unpublished data on human mitochondrial DNA variation. |
| NCBI Genome Viewer | Detailed views of the complete genomes of selected organisms from vertebrates to protozoa. |
| UCSC | UCSC Genome Browser; reference sequences and working draft assemblies for a large collection of genomes. |
| DNA | |
|---|---|
| Ensembl | Transcript-based views for coding and noncoding DNA. |
| NCBI RefSeq | A collection of genome, gene, and transcript sequence data from several sources, including GenBank, RefSeq. |
| UCSC | UCSC Genome Browser; reference sequences and working draft assemblies for a large collection of genomes. |
| Protein | |
|---|---|
| HPRD | The Human Protein Reference Database; manually extracted and visually depicted information on human proteins. |
| Human Protein Atlas | The Human Protein Atlas contains information for a large majority of all human protein-coding genes regarding the expression and localization of the corresponding proteins based on both RNA and protein data. |
| UniProt | Comprehensive protein sequence and functional information, including supporting data. |
| Gene Info | |
|---|---|
| Alliance Genome | Search Across Species; explore model organism and human comparative genomics. |
| BioGPS | The Gene Portal Hub; customizable portal of gene and protein function information. |
| Ensembl | Orthologs, paralogs, regulatory regions, and splice variants. |
| GeneCards | The Human Genome Compendium; web-based cards integrating automatically mined information on human genes. |
| Gene Ontology | Terms, defined using controlled vocabulary, representing gene product properties (biologic process, cellular component, molecular function) across species. |
| HGNC | HUGO Gene Nomenclature Committee. |
| KEGG | Kyoto Encyclopedia of Genes and Genomes; diagrams of signaling pathways. |
| MARRVEL | Model organism Aggregated Resources for Rare Variant ExpLoration. |
| Monarch | Monarch Initiative. |
| NCBI Gene | Gene-specific map, sequence, expression, structure, function, citation, and homology data. |
| PharmGKB | Pharmacogenomics Knowledge Base; curated and annotated information regarding the effects of human genetic variations on drug response. |
| UCSC | UCSC Genome Bioinformatics; gene-specific structure and function information with links to other databases. |
| Clinical Resources | |
|---|---|
| Alliance Genome | Search Across Species; explore model organism and human comparative genomics. |
| ClinGen Dosage | A ClinGen curated resource of genes and regions of the genome that are dosage sensitive and should be targeted on a cytogenomic array. |
| ClinGen Validity | A ClinGen curated resource of ratings for the strength of evidence supporting or refuting the clinical validity of the claim(s) that variation in a particular gene causes disease. |
| ClinicalTrials.gov | A registry of federally and privately supported clinical trials conducted in the United States and around the world. |
| DECIPHER | Database of chromosomal aberration including clinical and genomic information. |
| EuroGentest | A list of European laboratories that offer genetic testing. |
| Gene Reviews | Expert-authored, peer-reviewed descriptions of inherited disorders including the uses of genetic testing in diagnosis, management, and genetic counseling. |
| Genetic Alliance | Network of disease-specific advocacy organizations, universities, private companies, government agencies, and public policy organizations. |
| GTR | Genetic Testing Registry. |
| MedlinePlus Genetics | Consumer-friendly information about the effects of genetic variation on human health. |
| Newborn Screening | Information and resources for newborn screening and genetics. |
| OrphaNet | European reference portal for information on rare diseases and orphan drugs. |
| POSSUM | A dysmorphology database of multiple malformations; metabolic, teratogenic, chromosomal, and skeletal syndromes; and their images. |
| Variation | |
|---|---|
| ClinVar | ClinVar aggregates information about sequence variation and its relationship to human health. |
| gnomAD | The Genome Aggregation Database (gnomAD), Broad Institute. |
| GWAS Catalog | GWAS Catalog; NHGRI-EBI Catalog of published genome-wide association studies. |
| GWAS Central | GWAS Central; summary level genotype-to-phenotype information from genetic association studies. |
| HGMD | Human Gene Mutation Database; published mutations causing or associated with human inherited disease; disease-associated/functional polymorphisms. |
| inSIGHT | International Society for Gastrointestinal Hereditary Tumors. |
| Locus Specific DBs | A gene-specific database of variation. |
| NHLBI EVS | National Heart, Lung, and Blood Institute Exome Variant Server. |
| Animal Models | |
|---|---|
| FlyBase | A Database of Drosophila Genes and Genomes. |
| IMPC | International Mouse Phenotyping Consortium. |
| MARRVEL | Model organism Aggregated Resources for Rare Variant ExpLoration. |
| MGI Mouse Gene | Mouse Genome Informatics; international database resource for the laboratory mouse, including integrated genetic, genomic, and biological data. |
| MGI Mouse Phenotype | Phenotypes, alleles, and disease models from Mouse Genome Informatics. |
| MMRRC | Mutant Mouse Resource & Research Centers. |
| NCBI Orthologs | Orthologous genes at NCBI. |
| OMIA | Online Mendelian Inheritance in Animals (OMIA) is a database of genes, inherited disorders and traits in 191 animal species (other than human and mouse.) |
| OrthoDB | Hierarchical catalogue of orthologs. |
| Wormbase Gene | Database of the biology and genome of Caenorhabditis elegans and related nematodes. |
| ZFin | The Zebrafish Model Organism Database. |
| Cell Lines | |
|---|---|
| Coriell | Coriell Cell Repositories; cell cultures and DNA derived from cell cultures. |
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